Connect with others who understand.

  •   Learn from expert-reviewed resources
  •   Real advice from people who’ve been there
  •   People who understand what you’re going through
Sign Up Log In
All Resources Treatments A-Z Personal Assistant Help Center Crisis
Powered By
Real members of DiabetesTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

How do drugs like Jardiance and Farxiga protect kidneys?

A DiabetesTeam Member asked a question 💭
Rocky Face, GA
August 6, 2025
 · 
Reactions

Answer Summary

Members shared their personal experiences with SGLT-2 medications like Jardiance and Farxiga, celebrating impressive A1C levels ranging from... Read more

Members shared their personal experiences with SGLT-2 medications like Jardiance and Farxiga, celebrating impressive A1C levels ranging from 5.7 to 5.9 and noting that these drugs work by eliminating sugar through urination, which can lower fasting blood sugar significantly and support chronic kidney disease management. Several members described increased urination frequency, especially at night, with the practical tip to take the medication in the morning to minimize overnight bathroom trips. A recurring theme was that while these medications work exceptionally well for many, about 30% of members cannot tolerate them due to serious side effects like chronic yeast infections, UTIs, and other complications, underscoring the importance of individual response and close monitoring.

DiabetesTeam

SGLT2 inhibitors like Jardiance and Farxiga work by helping your kidneys remove excess sugar through your urine. This mechanism helps protect your kidneys in two important ways:

1. By reducing blood sugar levels, which helps prevent damage to blood vessels in the kidneys
2. By decreasing the workload on your kidneys' Show Full Answer

SGLT2 inhibitors like Jardiance and Farxiga work by helping your kidneys remove excess sugar through your urine. This mechanism helps protect your kidneys in two important ways:

1. By reducing blood sugar levels, which helps prevent damage to blood vessels in the kidneys
2. By decreasing the workload on your kidneys' filtering system For people with diabetes who develop severe kidney problems, treatments like dialysis may become necessary. However, medications like SGLT2 inhibitors can help protect kidney function when used as part of a comprehensive treatment plan that includes proper blood sugar management.

Always work closely with your healthcare provider to monitor your kidney function and adjust your treatment plan as needed.

August 6, 2025
A DiabetesTeam Member

@A DiabetesTeam Member you are not alone - about 30% of Jardiance and Farxiga users have to stop taking it due to serious side effects

For those that can tolerate the stuff it's a great drug class - for those that can't they get chronic yeast infections, UTI's and can even develop gangrene in places you never want to get it 😁

August 7, 2025
A DiabetesTeam Member

I was not allowed to take jaurdance bad reaction to it

August 7, 2025
A DiabetesTeam Member

I take Jardiance and my A1c is a 5.7 and it helps with my Chronic Kidney Disease.

August 7, 2025
A DiabetesTeam Member

Hugs to GrayhamLamb for comments to MargaretMErnenwein

August 7, 2025

Related Questions

View All

What do the doctors tell you to protect your kidneys?

A DiabetesTeam Member asked a question 💭
River Drive Park; Ontario Canada
February 5, 2023

Metformin

A DiabetesTeam Member asked a question 💭
Kings Lynn
July 14, 2018

Protecting Your Kidneys With Diabetes: A Visual Guide
How Do Carbs Affect Blood Pressure in Diabetes?
How Do Sulfonylureas Work for People With Diabetes?