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... The longest-acting insulin currently available is degludec (Tresiba). It can last up to 42 hours. It’s important to note that it may not last that long for you. Keep in mind that reaching steady-state (the blood concentration plateau) takes three to four days, so the dose should only be increased after four days. ...
Long-Acting Insulin for Diabetes: 8 Facts To Know
... The longest-acting insulin currently available is degludec (Tresiba). It can last up to 42 hours. It’s important to note that it may not last that long for you. Keep in mind that reaching steady-state (the blood concentration plateau) takes three to four days, so the dose should only be increased after four days. ...