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Real members of DiabetesTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

I am an insulin dependent diabetic. 50 U of Levemir in the AM, 39 at HS. I am about out of Levemir and am Allergic to Lantus. Dr is considering Trejoho (sp?) What's the likelihood of being allergic to it? I am terrified to change,

July 25, 2025
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DiabetesTeam

It's understandable to feel anxious about changing insulin medications, especially with a history of allergic reactions. While it's impossible to predict individual allergic responses to new medications, your healthcare provider will carefully monitor your transition to the new insulin.

Before starting any new insulin Show Full Answer

It's understandable to feel anxious about changing insulin medications, especially with a history of allergic reactions. While it's impossible to predict individual allergic responses to new medications, your healthcare provider will carefully monitor your transition to the new insulin.

Before starting any new insulin, make sure to:
- Inform your doctor about all previous allergic reactions
- Discuss your concerns openly with your healthcare team
- Ask about monitoring protocols during the transition
- Learn about potential side effects to watch for Remember that individual responses to insulin products can vary, and your healthcare team will work with you to find the right option. They may start with a lower dose and gradually adjust it based on your response. If you experience any concerning symptoms after starting the new insulin, contact your healthcare provider immediately.

July 25, 2025
A DiabetesTeam Member

@A DiabetesTeam Member Toujeo is a "synthetic" insulin just like Lantus so depends what it is that you are allergic to

You could always ask your Doc about the Human Recumbent Insulins Humulin N or Novolin N - these are 99.8% real human insulin so nothing to be allergic to unless it's that 0.2% preservative

These are the closest you will find to "generic" insulins, they are less expensive then the synthetics but a little less protection built in if you give yourself a slight overdose - the synthetics give you a little protection against a dosing "oops" within reason, the (naturals) are not forgiving like that which is why the newer recipes are more often prescribed

July 25, 2025

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