I take glimerpiride 4 mg along with. 500 mg metformin 2x a day. Also take 2 other 500 Mg Metformin s as well. A total of 2000 Mg Metformin a day and 8 Mg of Glimepiride.

@A DiabetesTeam Member same here. The glimerpride with all the other meds

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A Diabete...

I am taking 4mg of glimiepiride.

Thank you for the information. I am glad to learn more about what I am taking. Glimiepiride is what I am taking.

Amaryl is just a brand name of an older Sulfonylurea class drug called Glimepiride (came on the market in the 1970's) which a couple of members here are taking

It works exceptionally well at forcing your pancreas to release more insulin of course with the assumption that you are able to produce it

It is a second generation version in the drug class but it is still well known to cause low blood sugar, sometimes to dangerous/deadly levels if the user is not super vigilant in taking it exactly as prescribed

Sulfonylurea's or SU's can be somewhat cumbersome to take

They work best if you take them exactly as prescribed (1 hour before eating, every morning at 8 am or whatever), never skip a meal, try to keep the number of carbs in "every meal" similar, eat at the same time everyday even if that means you drop whatever you are doing to eat at noon (or whatever)

If you don't, you can go dangerous low - these are not the "take it and forget it" type meds like the new ones on the market today (Tradjenta, Ozempic, Rybelsus etc)

But they also don't cost a grand a month - in their generic form (simply called Glimepiride), even in the US with it's catastrophic drug costs, a months worth sells for about 20 bucks (without insurance)

The only known side effect (and these have been around for over 40 years in wide use) is possibly some weight gain - if that becomes apparent it is simply telling the user that they are eating too many carbs and need to dial them back a little

But the drug is awesome at dropping blood sugar using your "own insulin" to do it (if you are still producing enough)

The current guidance is that SU's users "should wear" a CGM sensor to protect against the lows and most insurance will cover CGM's for both Insulin and SU's users - which is the one positive