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My son is in the 5.8 pre diabetic range. His tummy is really causing him distress from Metformin. I asked his doctor about trying berberine. She said absolutely. Since he is pre diabetic

2 days ago
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DiabetesTeam

It's great that his doctor is on board — that's always the best starting point! Berberine patches are a newer delivery method, and there isn't much specific research on them yet. Most of the studies on berberine have been done using oral supplements, so it's hard to say how well the patch form compares.

That said, here's Show Full Answer

It's great that his doctor is on board — that's always the best starting point! Berberine patches are a newer delivery method, and there isn't much specific research on them yet. Most of the studies on berberine have been done using oral supplements, so it's hard to say how well the patch form compares.

That said, here's what research on berberine (in general) suggests for blood sugar and insulin resistance:

- It may help lower fasting blood sugar levels
- It has shown improvements in insulin sensitivity, meaning cells respond better to insulin
- In some studies, it reduced A1c by about 1 percent
- It may work similarly to metformin in some ways, though it is not FDA-approved as a diabetes treatment
- It may also help improve cholesterol and triglyceride levels One thing worth knowing is that berberine activates something called AMPK — think of it as the body's "energy controller" — which helps cells use sugar more efficiently and reduces sugar production in the liver. These are real, studied effects.

However, there are some important cautions to keep in mind:

- Berberine can interact with other medications, so his doctor should review everything he takes
- It can still cause digestive side effects like nausea, diarrhea, or constipation (a bit ironic given the reason for switching!)
- "Natural" doesn't automatically mean safe or side-effect free
- Supplement quality can vary — too much or too little of an ingredient is a real risk
- More large-scale, long-term human studies are still needed Since his doctor has given the green light, it's worth asking her specifically about the patch form versus oral berberine, and whether the dosage on the patch is appropriate. Keeping track of his blood sugar readings while trying it will also help show whether it's making a real difference.

2 days ago
A DiabetesTeam Member

Thank you for that @A DiabetesTeam Member

2 days ago
A DiabetesTeam Member

I took the Berberine tablets I did great for four months my sugar was excellent. But then I started to get anxiety very bad and I researched it and found out if
You are on any antidepressants etc. Tou shouldn’t take it . But it worked very well

2 days ago
A DiabetesTeam Member

He doesn't take any other meds. He was taking off of the levothyroxin for his thyroid as his thyroid numbers are great.

2 days ago

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