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Real members of DiabetesTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A DiabetesTeam Member asked a question 💭
Palmer, AK
April 14, 2025
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DiabetesTeam

What are the concerns about taking Metformin?

While Metformin is one of the most commonly prescribed and generally safe medications for type 2 diabetes, like all medications, it can have side effects. The most common side effects are gastrointestinal issues including nausea, diarrhea, constipation, and abdominal pain.

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What are the concerns about taking Metformin?

While Metformin is one of the most commonly prescribed and generally safe medications for type 2 diabetes, like all medications, it can have side effects. The most common side effects are gastrointestinal issues including nausea, diarrhea, constipation, and abdominal pain.

It's important to note that many side effects are temporary and often improve as your body adjusts to the medication. Working with your healthcare provider to find the right dosage and taking Metformin with meals can help minimize these effects.

Never stop taking Metformin without consulting your healthcare provider first. If you're experiencing troublesome side effects, they can adjust your dosage or consider alternative treatment options. They may also recommend taking an extended-release version of Metformin which can be easier on your digestive system.

April 14, 2025
A DiabetesTeam Member

Thank you so so much for all this information. I was starting to doubt using Metformin because of all the negative talk about Metformin. I am using the 500mg twice daily,but I think it also gives me some 'hot flushes'. But I am very grateful for the knowledge I received from you now, thank you!

April 15, 2025
A DiabetesTeam Member

Metformin was derived from a herb called french lilac. The active ingredient was synthesized in a lab. Metformin has a long history of use and many benefits.

Yes metformin is not natural to our bodies. Stomach issues can surface for about 2-3 weeks when beginning treatment and when increasing dosages.

Remember to ask for the extended release version called Metformin XR. Easier on the stomach.

But the benefits are many.

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Benefits of Metformin:

Lowering Blood Sugar:

Metformin is effective at lowering blood sugar levels in people with type 2 diabetes.

Weight Loss:

It can aid in weight loss by improving insulin sensitivity, reducing appetite, and potentially helping the body store less fat.

Improved Cardiovascular Health:

Metformin may reduce the risk of cardiovascular disease by improving blood vessel function and reducing the severity of heart attacks in animals.

Fertility:

Metformin can improve fertility in females with insulin resistance associated with PCOS and in obese males with reduced fertility.

Potential Anti-Aging Effects:

Some studies suggest that metformin may slow down the aging process and increase lifespan.

Reduced Risk of Certain Cancers:

Metformin may lower the risk of certain cancers, such as breast, colon, and prostate cancer, in people with type 2 diabetes.

Potential Anti-Inflammatory Effects:

Metformin may help reduce inflammation in the body.

Improved Cognitive Function:

Some studies suggest that metformin may be associated with less cognitive decline and a lower risk of dementia.

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Metformin does not cause kidney disease. It protects against kidney disease by lowering your numbers a bit. Glucose spikes cause cumulative vascular damage. That vascular damage causes and adds to diabetes complications and comorbidities.

Such as peripheral neuropathy, retinopathy, kidney disease, heart disease, blindness, brain damage, and more including death.

If you keep your numbers in the nondiabetic range of 4.0(72 usa) to 7.8(140 usa), you arrest that vascular damage right where it is now. You will not add to that cumulative vascular damage.

These are the facts.

Good luck.

April 15, 2025 (edited)
A DiabetesTeam Member

All medications have side effects. Your doctor considered that the benefits out weighed the side effects

April 15, 2025

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