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Real members of DiabetesTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A DiabetesTeam Member asked a question 💭
Dundee, UK

I've added a picture of an injection site 2 days after injecting. This was a pain free injection. I have similar on my stomach and they fade away after 3/4 days. The red circle is a little raw to touch but nothing serious.
Is this OK.
Still learning
I'm on 1 injection of Humulin (24 clicks) a day.

February 2, 2025
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A DiabetesTeam Member

@A DiabetesTeam Member each (brand) of Insulin is upwards of 99.8% "identical" to human insulin we produce ourselves, so it is beyond rare to get a reaction from the insulin itself

But that "little bit" is the specific preservative that the mfg uses and it's that preservative which can result in injection site irritation

The (irritation) is likely not dangerous but could be "pesky" so I would discuss it with the prescribing Doctor as there is a couple of (identical) alternatives which may alleviate the issue

If you are using Humulin N there is two alternatives, Novolin N and NPH which use different preservatives and may not cause the reaction

If you are using Humulin R then Novolin R is the direct alternative

February 2, 2025
DiabetesTeam

It’s common to experience minor redness or irritation at injection sites when using insulin like Humulin. These reactions usually fade within a few days, as you described. However, if the redness worsens, becomes painful, or doesn’t improve, it’s important to consult your doctor. Rotating injection sites can help reduce Show Full Answer

It’s common to experience minor redness or irritation at injection sites when using insulin like Humulin. These reactions usually fade within a few days, as you described. However, if the redness worsens, becomes painful, or doesn’t improve, it’s important to consult your doctor. Rotating injection sites can help reduce irritation and prevent issues like lipodystrophy. Always ensure proper injection technique and hygiene.

February 2, 2025
A DiabetesTeam Member

I’m on tresiba

February 3, 2025
A DiabetesTeam Member

@alankier that is an "L" type

So you are taking the "long acting" (Basil) Humulin so there is about a dozen alternatives that your doctor could swap this out with if you decide that the injection site discomfort is something you would rather not deal with and are willing to try a different brand

In terms of the popular types of Basil Insulin, the Humulin is NOT ONE of Them which is why I made the assumption you were on N or R

Lantus, Basaglar, Levemir and Tresiba combined probably have about 95% of the basil insulin market

February 2, 2025 (edited)
A DiabetesTeam Member

Looks like I'm on L

February 2, 2025

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