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Are There Any Diabetics Out There Who Carry A Thallasemia Trait? This Means That Hbaic Is Inaccurate And A Fructosamine Test Needs Doing.

Are There Any Diabetics Out There Who Carry A Thallasemia Trait? This Means That Hbaic Is Inaccurate And A Fructosamine Test Needs Doing.

My medical team do both the Hbaic and Fructosamine tests but tend to rely on the Hbaic to determine insulin dosages, diet and other advice. July hbaic was 8.8 and Fructosamine 298. Converted to hbaic this is 6.7. Test yesterday hbaic 9.3 and Fructosamine 313. Converted this is 6.9. This is a worrying discrepancy. I can't help wondering if the Lifetyle Libre arm sensor, given the Thallasemia trait is also accurate. Finger prick results are always a few points higher. I also suffer from CIPD and… read more

posted November 23
A DiabetesTeam Member

@A DiabetesTeam Member

It is known amongst diabetes experts (not the average Doctor) that the A1C test is inaccurate with certain people and certain racial groups due to genetic differences.

The Fructosamine test is a very accurate "short term" glance at sugar in your blood (about 2 weeks of history) while the A1C represents up to 3 "months" of blood sugar history so you need to be careful that you are not comparing apples to elephants - they give you different information.

The Libre is calculating blood sugar at the "cellular level" and not in your blood and so yes, a stick test is typically a "few points" Higher OR Lower then a Libre reading because it takes time for the sugar to migrate from your blood to your inter-cellular fluid that the Libre measures.

In fact if you had a blood draw (lab), did a stick test and scanned your Libre all the same minute the three of them would all be slightly different unless your blood sugar had been perfectly stable for about 15 minutes.

If it was rising slightly the Lab draw would be a few points higher then the stick test which would be a few points higher then the Sensor and that would be "normal and accurate".

If your Insulin dosage is not causing regular/dangerous lows then using A1C to calculate unit recommendations (at least in your case despite your different results) is working for you.

Insulin is one treatment that gives you "immediate feedback" if you are overdosing...

posted November 23 (edited)

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