Is Janumet a form of metformin or is from that group of medicines? If so, then you are suffering from flare-ups of IBS. I had to cut my metformin back as it was a trigger all the time for flash diarrhea and left me stranded at home all the time. So I would keep track of my symptoms and if they continue, you have to see your doctor or medical person who takes care of your diabetes care.

I use metformin 850 mg and don't increase because I suffer from severe Irritable Bowel Syndrome. I have been taking it since 2008 and my issues aren't kidneys; they are fatty liver disease and fatty pancreas.

Metformin is really bad for damaging the kidneys. Make sure your doc is monitoring your creatinine every 3 months!

I used to take metformin on its own and it was deadly! Had to stop taking it. Your med is Januvia and Metformin combined in 1 pill.