Thank you. The more you know, the better off you are. Knowledge is power.

@A DiabetesTeam Member, @A DiabetesTeam Member, thank you for these insights and information. What I just read from you both and DT researchers are very helpful and an eye opener. I can relate my paternal grandmother and some of her cousins, Uncle, 3-4 cousins, 2 siblings have DM and prediab conditions. So as a precaution, I researched, studied and joined Diabetes Team to delay or avoid diabetes issues. Thank you very much. Regards

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Gene testing, at least in the Diabetes world is used in Infants and Young Children to correctly Diagnose "Monogenic" forms of Diabetes including:

MODY or Mature Onset of Diabetes in the Young - One of 12 (so far) Inherited Genes that "genetically" cause diabetes that can range anywhere from diet/exercise only management to requiring Insulin to survive - depending on the exact gene causing the problem

OR

NDM or Neonatal Diabetes Mellitus - babies are born as (effectively) a Type 1 but it's a Genetic Disorder (NDM) and NOT Auto-Immune (Type 1)

Both types can only be confirmed by a Genetic (DNA) test

Type 1 and LADA (or Latent Auto-immune Diabetes in Adults) can "only" be confirmed with an "Antibody" Test

So not looking for a (defective) Gene but checking for the presence of the GAD or the Glutamic Acid Decarboxylase Antibody (aka GAD or GADA)

The presence of a "single" anti-body = LADA, the presence of "2 or more" different anti-bodies = Type 1

All other forms of Diabetes are metabolic in nature - there is no "gene or dna or anti-body test" (yet) to confirm but rather clinical diagnosis is any of:

2 X A1C tests, 90 days apart (minimum) where your A1C level is 6.5% or higher for Type 2 and 6.0-6.4% indicating Pre-Diabetes,

2 X FBS tests (Lab), 90 days apart where your FBS is greater than 126/7.0 mmols, or
(an FBS does not indicate Pre-Diabetes - it's either a Diabetic or Non-Diabetic Fasting Number although below 100/5.5 mmols is considered "Normal")

2 X OGTT (Oral Glucose Tolerance Tests) that measure Blood Glucose levels at 1, 2 and 3 hours after doing a "glucose shooter" of 75 or 100 (grams) of Glucose with results greater than 140/7.8 mmols at hour 2 and/or 3 indicating Type 2 - Pre-Diabetes is not diagnosed with an OGTT

(Ideally the Doc would Mix/Match two of the three tests to confirm the Type 2 Diagnosis since all three of them have their limitations)

Genetic Testing for Hereditary Type 2 Diabetes (for that 5-10% of Type 2's that fall under that sub-group) is still in it's infancy and while they have identified upwards of 100 "Genetic Loci" - genes that attach to our chromosomes and increase our risk factors - they are still years away from any kind of effective and simple test that could give certain individuals a "heads up" that for "them" it really is important to maintain weight and eat properly to prevent the Type 2 Diagnosis - maybe One Day, but not today, but they do "know" that it is "multiple genes" that cause Hereditary Type 2 and it's not a single factor that can prevent it...

To know about some ailment that runs in your family@ Joyce586

Thank you