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Real members of DiabetesTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Taking Dococyline

A DiabetesTeam Member asked a question 💭
Calig

I will be on Dococycline for the rest of my life. I keep getting huge drops in my blood sugar. I take no other diabetes medicines. Just wondering if anyone had any suggestions .
Thanks

May 4, 2022
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Answer Summary

Members confirmed that doxycycline can significantly lower blood sugar levels due to its effects on insulin resistance, validating the... Read more

Members confirmed that doxycycline can significantly lower blood sugar levels due to its effects on insulin resistance, validating the experience of someone managing both a lifelong bone infection and diabetes without other diabetes medications. Several members recommended using a continuous glucose monitor like Libre or Dexcom for constant monitoring and carrying glucose tablets to prevent dangerous lows, though the original poster shared that insurance does not cover a CGM and they must rely on frequent finger-prick testing instead. A recurring theme was frustration with insurance companies denying coverage for helpful monitoring tools, balanced with practical advice to test frequently and protect against low blood sugar as if using insulin.

A DiabetesTeam Member

Perhaps your two doctors could work on your situation together. I use a cgm for my diabetes and find it very helpful to be able to monitor my bg as frequently as needed.

May 4, 2022
A DiabetesTeam Member

A couple of studies were conducted to see if Dococyline could be used to improve insulin resistance since it is an anti-inflammatory anti-biotic.

All of the published results showed that at low dose it had a notable effect on lower blood sugar levels through improvement of insulin resistance.

(I have no idea what "low dose" means other than it was at a non-therapeutic level - so not enough for the "on-label" diseases it is meant to treat, but somewhat "less" just to see if they could effect blood sugar)

So if you are on a dosage that is being used to treat one of it's approved uses you could well see significant blood sugar swings.

To combat that you would essentially have to test/protect "as if" you were an insulin or sulfonylurea user that was prone to dangerously low blood sugars.

You might be well served to get use a CGM such as Libre or Dexcom to keep a constant watch on your blood sugar levels and carry glucose tablets to treat if it starts going too low.

May 4, 2022
A DiabetesTeam Member

Do you mean Doxycycline the Tetracycline Antibiotic? If so, it can definitely impact your bg. You should bring this up with your doctor.

May 4, 2022
A DiabetesTeam Member

Oh
Yes I understand now

May 29, 2022
A DiabetesTeam Member

I'm not asking anything. Just my comment on Insurance companies.

May 29, 2022

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