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A DiabetesTeam Member asked a question 💭
Ottawa, ON
September 1, 2021
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Answer Summary

Members shared their experiences taking four Metformin tablets daily, with many reporting success in lowering their A1C levels from dangerous... Read more

Members shared their experiences taking four Metformin tablets daily, with many reporting success in lowering their A1C levels from dangerous ranges (like 13) down to well-controlled numbers (between 5 and 8), though some found their glucose levels rose again when doctors tried reducing the dose back to two tablets. Several members described combining maximum-dose Metformin with lifestyle changes like low-carb diets and daily exercise, as well as additional medications like glipizide, to achieve better control and avoid insulin. A recurring theme was the shared goal of staying off insulin and the satisfaction of seeing hard work pay off in lower A1C numbers and reduced risk of complications.

A DiabetesTeam Member

@A DiabetesTeam Member how effective was that on improving your A1C.

I read a study done by Johns Hopkins and they found a maximum dose (4 tablets or 2000 mg daily) showed an average reduction of 1.5%.

Was wondering if you saw better results or it the Doc also adjusted/added other meds.

September 10, 2021
A DiabetesTeam Member

So you are probably close to a maximum dose.

Most doctors consider 2000 mgs (4 x 500 mg tablets) to be "the maximum" but some will treat up 2550 mgs because there is 850 mg tablets with 3 being the max dose according to the mfg.

Unfortunately when a max dose of Metformin is still not achieving "fasting target" (because that's what metformin treats, not after meal numbers) then the next step is almost always a Basil (long acting) Insulin.

September 1, 2021
A DiabetesTeam Member

I started out with 4 metformin a day but issues with my balance caused me to cut back to 3 a day,thinking about going back to 4 a day.

November 7, 2021
A DiabetesTeam Member

I take 4 tablets of metformin a day. Had a 5.7 a1c a month ago. I also take 2.5 mg of glipizide at night

November 6, 2021
A DiabetesTeam Member

That's excellent @A DiabetesTeam Member

That means you are "clinically" pre-diabetic.

You want to watch that - it could turn into Diabetes some day 😂

More seriously, doesn't it feel just great - a mental victory - when you work hard and get your A1C out of the Diabetes range.

You really kicked the "complications can" pretty far down the road with that number - well done.

October 10, 2021

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