Glyburide, Glipizide and Glimeperide, all Sulfonylurea (SU) class drugs, along with Metformin make up the "Top 4" in the US (which probably means most of the western countries as well).

And that makes total sense.

Those 4 have been around, as a pharmaceutical (product) for about 100 years, they all "work well" and they have "always been" generic.

In Ontario a months worth of Glyburide or Metformin runs about 20 bucks (depending on the lab that produces it).

Compare that to a months worth of Ozempic at $1200.

I been on 500 ml twice a day on metformin since l been a diabetic and have had no problems but I also eat healthy low calories and exercise every day if this helps you out some

Synjardy ( it has metformin in it and empagliforzin ) , is a wonderful medication. I have been on it for a couple of years. It has helped me lose weight and helps with sugars.

Just started Synjardy and discontinued Janumet and Jardiance. I will take this win. Sugars seem to be a litte better controlled.