Glumetza is usually not the original cause of kidney problems. However, glumetza is eliminated by the kidneys and when a patient has poor kidney function, the glumetza can build up in the blood and cause a rare but serious condition called lactic acidosis. Lactic acidosis affects the chemistry balance of your blood and can lead to kidney failure and other organ failure. The risk of lactic acidosis is very low and most often occurs in patients with poor kidney function - so for most patients, the benefits of glumetza outweigh the risks of treatment. Most doctors will regularly perform kidney function tests to make sure the kidney is working well in patients who are taking glumetza.

if you are worried about your kidney function ask your doctor to check your BUN and creatinine and then go over the results with you.

Nausea, strong urine, not emptying bladder all the way and the kidney is sore to touch.

Talk to your Dr. About your Meds .And find out the side affects of your meds

With that said, if you are taking glumetza, contact your doctor immediately if you experience unexplained weakness, muscle pain, difficulty breathing, or increased drowsiness - these can be early signs of lactic acidosis. Also, if you are taking glumetza and going to receive a radiocontrast dye study or have surgery, tell your doctors that you are taking metformin - in most cases, your doctor will instruct you to temporarily stop taking glumetza during these procedures to help decrease the risk of lactic acidosis.